Ai KOHATA, PhD
Assistant Professor, School of Life Science and Engineering, Tokyo Institute of Technology
E-mail:aikohata [at] bio.titech.ac.jp
ORCiD:0000-0003-2019-559X
Researcher Number:30851852(researchmap)
Field of Study:Chemical Biology, Supermolecular Chemistry, Fluoroorganic Chemistry
Education
2019-2022 Ph.D. (Engineering), The University of Tokyo
Thesis: Molecular Glues for Nucleic Acids in Biomedical Applications
Supervisor: Prof. Takuzo Aida
2017-2019 M.S., The University of Tokyo
2013-2017 B.S., The University of Tokyo, Supramolecular chemistry and chemical biology,
Advisor: Prof. Takuzo Aida
Professional Appointments
2023/07–Present Assistant Professor, School of Life Science and Engineering, Tokyo Institute of Technology
2022/04–2023/06 Project assistant professor, The University of Tokyo
2019/04–2022/03 Japan Society for the Promotion of Science (JSPS) research fellow
Publications (Original Paper)
Koji Kadota, Toshiki Mikami, Ai Kohata, Jumpei Morimoto, Shinsuke Sando, Kohsuke Aikawa,* and Takashi Okazoe
Chembiochem. 2023, e202300374.
3. Reconstitution of Microtubule into GTP-Responsive Nanocapsules
Noriyuki Uchida, Ai Kohata, Kou Okuro, Annalisa Cardellini, Chiara Lionello, Eric A. Zizzi, Marco A. Deriu, Giovanni M. Pavan, Michio Tomishige, Takaaki Hikima, Takuzo Aida*
Nat. Commun. 2022, 13, 5424.
Ai Kohata, Ryosuke Ueki, Kou Okuro,* P. K. Hashim, Shinsuke Sando, and Takuzo Aida*
J. Am. Chem. Soc. 2021, 143, 13937–13943.
1. Transferrin-Appended Nanocaplet for siRNA Delivery into Deep Tissues
Ai Kohata, P. K. Hashim, Kou Okuro,* and Takuzo Aida*
J. Am. Chem. Soc. 2019, 141, 2862–2866. (selected as “Front Cover”)
Book
第6章 第8節 ペルフルオロ構造を利用したペプチドや核酸の細胞内送達技術. 『新規モダリティ医薬品のための新しいDDS 技術と製剤化』
岡添隆, 相川光介, 木幡愛
(株)技術情報協会, 東京(2023年1月31日), p 325–332.
Patent
(1)「フルオロアルケン共重合体」
発明者: 柏木王明、岡添隆、杉山徳英、秋山みどり、木幡愛、増田潤季、奥田瑞来
出願人: 国立大学法人東京大学、AGC 株式会社
特願 2022-175052, 2022.10.31
(2)「コンジュゲート用細胞膜透過性ペプチド」
発明者: 柏木王明、岡添隆、相川光介、山東信介、森本淳平、木幡愛、門田晃司
出願人: 国立大学法人東京大学、AGC 株式会社
特願 2022-170448, 2022.10.25
(3)「トランスフェクション用核酸」
発明者: 岡添隆、相川光介、岡本晃充、森廣邦彦、木幡愛
出願人: 国立大学法人東京大学、AGC 株式会社
特願 2023-033984, 2023.03.06
(4)「含フッ素化合物」
発明者: 太田有羽、岡添隆、相田卓三、ゴスワミ・アビール、木幡愛
出願人: 国立大学法人東京大学、国立研究開発法人理化学研究所、AGC 株式会社
特願 2024-072312, 2024.04.26
Awards
2023/10 Excellent oral presentation award, The 46th Fluorine Conference o Japan
2022/11 ISNAC outstanding poster award in 2022, the 49th International Symposium on
Nucleic Acid Chemistry (ISNAC)
2022/09 The L'Oréal-UNESCO for women in science Japan fellowships 2022
2022/03 Chemical Society of Japan (CSJ) student presentation award, the 102th CSJ annual meeting
2022/03 Dean’s award, graduate school of engineering, the University of Tokyo
2022/03 Best team presentation award, JSPS 13th HOPE meeting
2021 Funakoshi Ryuta award, Funakoshi Co., Ltd.
2020 First Prize, Idea pitch contest, Johnson and Johnson K. K.
2019/03 Best presentation award, 139th annual meeting of the pharmaceutical society of Japan
2019/03 Dean’s award, graduate school of engineering, the University of Tokyo
2018/12 The 12th SPSJ International Polymer Conference, IPC2018 Young Scientist Poster Award
2016 Best presentation award, OIST science challenge workshop 2016
Grants-in-Aid for Scientific Research
2023/04–2025/03 Grant-in-Aid for Early-Career Scientists(Representative)
2019/04–2022/03 Japan Society for the Promotion of Science (JSPS) research fellow (Representative)
Research Grants
2023/04–2025/03 The Kao Foundation for Arts and Sciences, The 2nd Kao Crescent Award